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Sodium Cridanimod

CAS No. 58880-43-6

Sodium Cridanimod( XBIO-101 | XBIO101 | Cridanimod sodium )

Catalog No. M15173 CAS No. 58880-43-6

A potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.

Purity : >98% (HPLC)

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Biological Information

Product Name

Sodium Cridanimod
Note

Research use only, not for human use.
Brief Description

A potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.
Description

A potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route; displays extraordinary activity in phosphorylating IRF3 in the murine system; also increases progesterone receptor (PrR) expression in endometrial tissue.Ovarian Cancer Phase 2 Clinical.
In Vitro

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In Vivo

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Synonyms

XBIO-101 | XBIO101 | Cridanimod sodium
Pathway

Immunology/Inflammation
Target

STING
Recptor

STING
Research Area

Cancer
Indication

Ovarian Cancer

Chemical Information

CAS Number

58880-43-6
Formula Weight

276.247
Molecular Formula

C15H11NNaO3
Purity

>98% (HPLC)
Solubility

——
SMILES

C1=CC=C2C(=C1)C(=O)C3=CC=CC=C3N2CC(=O)[O-].[Na+]
Chemical Name

2-(9-oxoacridin-10(9H)-yl)acetic acid, sodium salt

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Cavlar T, et al. EMBO J. 2013 May 15;32(10):1440-50. 2. Zhang H, et al. Sci Rep. 2015 Dec 16;5:18035.

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